The main ingredient in Apcalis Jelly is tadalafil, which is also the active ingredient in Cialis. The pharmaceutical patent for this medication reached its expiry date in the UK on 14 November 2017. This allowed generic manufacturers in the industry the opportunity to produce and sell this treatment at substantially lower prices. You can now buy Apcalis Oral Jelly from our online pharmacy today and expect significant cost savings.
Apcalis Oral Jelly 20 mg is used by men worldwide to help them achieve firm erections, thereby enhancing their overall sexual confidence. This medication can be taken on an as-needed basis and stays effective for considerably longer than other medications which are frequently used for erection difficulties. For this reason, Apcalis Oral Jelly is now used by an increasing number of men and is often the preferred choice of treatment.
Apcalis Jelly is a popular and easy-to-use treatment for erectile dysfunction, or ED. This condition involves a long-term lack of ability to get or maintain an erection that is suitable for satisfactory sexual activity. These jellies are particularly suited to men who prefer a trouble-free route of administration compared to the tablet form. There is a 20 mg dose of tadalafil contained in each flavoured jelly that can be taken about half an hour before planned sexual activity.
To gain a better understanding of ED, it may be helpful to know how an erection happens. During sexual arousal, certain enzymes in the body work together to relax and dilate blood vessels in the penis. Thereafter, blood flows efficiently into the two spongy rods that extend the length of the penis (corpora cavernosa), causing an erection to form. The most common cause of ED is reduced blood supply to the penile region caused by problems with blood vessels.
Various conditions can lead to abnormal blood vessels and erectile dysfunction symptoms. Most often, ED is caused by physical health conditions like diabetes and hypertension. However, it can also be the result of emotional issues like anxiety. Anxiety about sexual performance can lead to the activation of stress hormones such as adrenaline, resulting in narrow blood vessels. Thankfully, medication like Apcalis Oral Jelly 20 mg has been shown to effectively treat ED due to both physical and psychological problems.
These jellies work by inhibiting the activity of a substance in the body called phosphodiesterase type 5, or PDE5. This substance is found in various parts of the body including the intestines, lungs and several tissues. It is found in especially high concentrations in the smooth muscle cells that line the blood vessels of the penis.
PDE5 degrades cyclic guanosine monophosphate (cGMP), which is an enzyme that is needed for healthy erectile function. cGMP improves the body's ability to produce nitric oxide which is a natural chemical that promotes the dilation of blood vessels. By inhibiting PDE5, this medication strengthens erections as it allows more blood to flow smoothly into the penis when sexual stimulation takes place.
Apcalis Jelly is fast acting as it is rapidly absorbed in the body so you can expect to experience the beneficial effects within 15-30 minutes. The jellies are easy to swallow and come in various flavours, making them ideal for people who have difficulty swallowing hard tablets. The recommended Apcalis Oral Jelly dosage is as follows:
It is also advisable to avoid consuming grapefruit juice when taking your tadalafil dosage. The reason for this is that grapefruit can increase levels of this medication in the bloodstream, resulting in an increased chance of side effects. It can also delay the absorption and onset of effects, potentially resulting in reduced efficacy.
This erectile dysfunction treatment is the market leader when it comes to how long it lasts. It has a durational efficacy of 36 hours, allowing plenty of time for couples to be spontaneous. It is important to note, however, that Apcalis Oral Jelly 20 mg does not induce an erection on its own. Just like if you were not taking erectile dysfunction tablets, there will need to be some type of sexual stimulation for it to work.
Before Apcalis Jelly in the UK was released, it was administered to more than 9,000 men in worldwide clinical trials. These trials are conducted to assess the safety and efficacy of medications before they can be sold. In eight of these studies, the average age of participants was 59 and the discontinuation rate due to side effects was 3.1% for tadalafil and 1.4% for placebo.
Placebo is a substance that has no pharmacological effect like sugar or starch. Therefore, the discontinuation rate due to adverse effects of this PDE5 inhibitor was almost the same as an inactive treatment, revealing the safety of this medicine. The following are common side effects:
Tadalafil side effects generally do not last longer than a few hours and they tend to be mild or moderate. In general, headaches are the most common side effect and can be managed in the following ways:
Although these jellies are safe for most people, there are certain patients who should avoid this medication or use it with extra caution. The following table contains the most common precautions associated with this ED treatment:
|When this medication is contraindicated||If you have an allergy to the medication, serious heart disease, low blood pressure or high blood pressure that is not controlled by medication.|
|When caution is advised||If you have sickle cell anaemia, multiple myeloma or leukemia. Caution is also advised in patients with liver or kidney problems as well as those with a condition called Peyronie's disease.|
|Other medications (interactions)||Avoid taking these jellies with other PDE5 inhibitors like Viagra and Levitra as they work in the same way so combining them increases the chance of side effects. Medications that are used to treat angina called nitrates should also be avoided as the interaction may lead to an abrupt drop in blood pressure. Alpha blockers like terazosin and doxazosin should also be avoided as the combination can cause a sudden decrease in blood pressure.|
The price of Apcalis Oral Jelly in the UK is a distinct benefit. Since the patent for this well-liked ED treatment came to an end, the price has decreased by up to 85%. Generic companies are able to offer their products at substantially lower prices because the regulatory authorities do not require them to replicate expensive clinical trials.
The safety and efficacy of this medication has already been demonstrated, so generic manufacturers simply use the same chemical formula to produce their medications. In addition to initial savings on research and development, generic producers are able to sell their medications at lower prices due to the following reasons:
It is important to note that the lower price does not mean the quality of generic products is compromised. Strict regulations that govern the generic industry require generic medications to be bioequivalent to their branded counterparts. For this reason, you can expect Apcalis Oral Jelly in the UK to have the same safety, therapeutic effects and side effects as the original branded version. Also, generic manufacturers are required to produce this medication in world-class facilities so you can expect premium-quality products when you order online.
These jellies have become so popular because they are easy to use and discreet. The gel-like substance can be conveniently taken with a spoon or straight from the sachet. Due to its long-acting duration of effect, Apcalis Oral Jelly is one of the most sought-after treatments for ED. Other PDE5 inhibitors like sildenafil and vardenafil only stay effective for about four hours.
With Apcalis Jelly, you can take a sachet on Friday afternoon and the effects may still be felt on Sunday. This long-acting ED treatment allows couples to participate in sexual activity at a natural time. As a result of the relatively low dose of the main ingredient, most people generally report little or no side effects when they buy Apcalis Oral Jelly.
A clinical trial was conducted to compare preference among patients for tadalafil 20 mg or sildenafil 50 mg in the initial treatment of ED. In addition, the tolerability of these medications was compared. Altogether, 215 men were involved in the research and they were randomly assigned to two groups. A total of 109 men received the active ingredient in Apcalis to take for four weeks followed by sildenafil. The remaining 106 men received sildenafil first to take for four weeks, followed by the active ingredient in Apcalis.
At the end of the trial, 190 participants were able to be evaluated and 126 (66.3%) preferred to start treatment with the active ingredient in Apcalis Jellies. Although some men preferred the short-acting effects of sildenafil, the long-acting effect of the active ingredient in Apcalis Jellies was preferred. Both treatments were well tolerated and there were no serious side effects reported by any of the study participants.
Apcalis Oral Jelly reviews are usually outstanding as this medication contains the exact same active ingredient as Cialis Most men who have used this medication report excellent results and claim it has helped them regain their sex lives. In general, this medication significantly improves sexual performance, which often has a positive effect on self-esteem and relationships among couples.
Apcalis Jelly in the UK can be taken as needed so these jellies do not have to be taken on a daily basis or regular schedule. In medical research, this medication has been shown to enhance erectile function in up to 81% of men who use it. It has been extensively tested in numerous clinical trials since its release in 2003. As a result, this ED treatment is well known by medical experts to have few troublesome adverse effects.
At www.kamagrauk1.com, there is a wide range of branded products and more affordable generic treatment options to choose from. In contrast to the high costs associated with land-based outlets, our prices are affordable as there are no additional markups due to high overhead expenses of land-based pharmacies.
We manage to keep prices up to 80-90% less than what you would pay at your local pharmacy - without cutting quality or service levels. We have long-standing relationships with generic producers and this helps ensure best value for our loyal customer base; we also buy in bulk and focus on a small margin only as our motive is to get treatment into the hands of all patients needing it - at the lowest prices.
You can buy Apcalis Jelly in the UK by visiting our website and following the convenient online order process. This removes the hassles of visiting a brick and mortar pharmacy like lack of privacy, long queues and closed shops. Our knowledgeable customer support representatives are available around the clock to offer help if have any questions. When you buy Apcalis Oral Jelly, you can be sure of premium-quality medications as all quality control measures are carefully adhered to.
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