Addyi

MANUFACTURER: SPROUT PHARMACEUTICALS, INC

A recent research study indicated that at least one third of women (aged 18 to 59) experienced an issue with low libido that was more serious than a simple lack of interest. There could be a variety of reasons contributing to this sexual disorder, ranging from physical or psychological but the symptoms of hypoactive sexual desire disorder (HSSD) can be effectively managed with the use of flibanserin (brand name, Addyi).

One of the most frequent conditions among women is low libido. While it is common for the sexual desire of women to fluctuate as they age, there are some instances where there is a drastic change in sexual arousal (such as none at all), which can be concerning

When sexual disorders or dysfunctions come to mind, many people relate these issues to the sexual health of men, but these conditions can be equally distressing for women as well. In fact, sexual dysfunctions, such as painful intercourse, little to no sex drive and difficulties reaching sexual climax are all common issues among the female population. Female sexual dysfunction does not have to be endured, especially for women who are pre-menopausal.

Addyi has been approved by the Food and Drug Administration (FDA) since August 2015 and can be used to increase the number of satisfying sexual activities experienced.

WHAT IS ADDYI?

Addyi tablets are an efficacious female sexual dysfunction treatment used by women who have not yet gone through menopause. The Addyi medicine has, however, not been indicated for women who are post-menopausal.

The reasons for women experiencing HSDD (and who may require Addyi treatment) may vary, as there are extensive possible female sexual dysfunction causes. Some of these include:

Physical causes

• Certain medicaments and treatments: there are certain medications which can adversely impact the sexual desire of a woman. Examples include SSRIs (selective serotonin reuptake inhibitors), which are antidepressant medicines that can cause negative side effects, such as low libido.
• Blood flow disorders: for sexual arousal to occur, there has to be adequate blood flow to the female genitalia. Disorders that interrupt the flow of blood to the vagina, labia or clitoris may result in symptoms of female sexual dysfunctions.
• Medical conditions: health conditions, such as diabetes, can affect the libido of women. It is the combination of the physical effects of the disease or condition, with the combination of the physiological effects of the condition that lead to the onset of sexual disorders.
• Hormonal changes: changes in the female hormones can result in vaginal dryness and hence, the ability of a woman to enjoy sex.

Psychological causes

• Stress: this is a major cause of low sex drive as the feelings of stress are able to alter the levels of the hormone, cortisol. Increased cortisol levels can reduce the ability of one to become aroused.
• Depression: this ailment can prevent one from enjoying certain activities that they previously found enjoyable, including sex. The negative feelings associated with depression can further contribute to female sexual dysfunctions.
• Low self esteem: hormonal surges can influence the emotional conditioning of a woman and with these changes there can also be negative implications on the sexual health of a female as well. Those with low self esteem are less likely to engage in sexual activity, and severe cases of negative self-image can contribute to female dysfunction disorders, such as a lack of sexual desire.

WHAT IS ADDYI USED FOR?

HSDD has been a recognised medical condition for over 39 years but it was removed from the Diagnostic and Statistical Manual of Mental Disorders in 2013 and replaced with a new diagnosis, known as female sexual interest/ arousal disorder, or FSIAD.

Addyi is used to treat women, who are specifically pre-menopausal, for the symptoms of HSDD or FSIAD.

Some of these female dysfunction symptoms include:

• A lack of interest in initiating sex
• A lack of interest in any sexual activity (little to none)
• Difficulties in experiencing pleasure from sex
• Lack of pleasure even through the stimulation of genitalia
• Little to no sexual fantasies or thoughts

Much like other medical conditions, there is no definitive diagnosis for this sexual disorder but you can be prescribed Addyi tablets if you meet the above criteria, and if the symptoms of HSDD/ FSIAD have severe and undesirable consequences on your sexual health and well-being.

HOW DOES ADDYI WORK?

• Addyi works in a manner similar to that of an anti-depressant medication or SSRI. An SSRI functions by altering the brain chemistry or more specifically, by influencing the levels of the hormones, serotonin and dopamine (mood regulator hormones).
• To increase sexual desire and hence, treat the symptoms of HSDD/ FSIAD, Addyi also alters the brain chemistry of a woman to balance the levels of certain neurotransmitters. Similar to SSRIs, Addyi tablets increase the levels of norepinephrine and dopamine, whilst reducing the levels of serotonin in the brain.
• The exact mechanism of Addyi is not well known but it is believed that by reducing the levels of serotonin, the hormone responsible for the inhibition of sex drive, the normal sexual desire functions of a female may be restored. Likewise, the enhanced levels of dopamine and norepinephrine can also increase libido in women.

HOW LONG WILL ADDYI LAST?

Addyi increases the sexual desire of a woman by affecting the key hormones in the brain but the effects of this medication can take up to four weeks before noticeable changes are observed. With that said, if there is no improvement after using Addyi sex pills for eight to twelve weeks, it is recommended that treatment be discontinued.

However, Addyi tablets for HSDD/ FSIAD have proven to be effective for many women. In a study (English et al., 2017) analysing the safety and efficacy of this medication, dosages of this therapeutic were administered to women that were pre-menopausal. And even though it may not be approved by the Food and Drug Administration (FDA), Addyi doses were given to women who were post-menopausal as well.

The results of this study were positive, in terms of the number of satisfying sexual experiences (SSEs), over a 28 day period. It was reported that the women in the treatment group (those given Addyi) showed significantly more SSEs over the 28 day period than those in the placebo group. These findings were the same for both the pre- and post-menopausal women as well.

ADDYI DOSAGE GUIDE

According to the previously mentioned study, the initial and generally advised dosage of Addyi should be 100 mg, prior to retiring to bed. These tablets may be administered with or without food, but should be taken with a drink of water.

Even though food may not be required for the functioning of these pills, administration of Addyi after a meal may increase the systemic absorption of the therapeutic.

These researchers went on to recommend that Addyi not be taken during the daytime as it increases the risk of hypotension (low blood pressure), syncope (fainting) and somnolence (excessive drowsiness or sleepiness).

Furthermore, evidence of this study indicated that if there are no visible improvements in the symptoms of HSDD/ FSIAD within eight weeks of using Addyi, then it is recommended that one stop the administration of these tablets.

It was also reported that the sedative effects of this therapeutic was dose-dependent. This means that higher dosages were associated with undesirable side effects, as compared to lower dose regimens. It is for this reason that the recommended dosages be adhered to so as to minimise the risk of unwanted adverse events.

POSSIBLE ADDYI SIDE EFFECTS

The most notable side effects of Addyi, in the clinical trials conducted by the manufacturer, were fatigue, dizziness, dry mouth and nausea. But, there is limited evidence regarding the severity of these adverse events.

However, should you find that any of these side effects are a little more than mild in nature; you can use the following ways to manage the symptoms:

• Fatigue: in clinical trials relating to the use of Addyi, in patients who were concomitantly using hormonal contraceptives, fatigue was reported by 11.4% of the clinical trial patients. For those not using the contraceptives in concordance with the HSDD/ FSIAD tablets, fatigue was experienced by 7.5% of the women.
  
  Fatigue is characterised by intense levels of reduced energy and an overall feeling of tiredness. To overcome these symptoms, you can try eating foods or drinking beverages known to increase energy levels. Some of these foods and drinks can include bananas, apples, eggs and coffee.
• Dizziness: women in the research studies pertaining to the adverse effects of this medication were reported as experiencing higher incidences of dizziness when taking the pills in conjunction with hormonal contraceptives.
  
  To assist in the management of dizziness symptoms, it is advised that one lay down and rest in a dark, quiet area. Drinking plenty of water can also assist in relieving dizziness.
• Dry mouth: in one study of the possible Addyi side effects, the event of dry mouth was reported by 2.4% of the trial patients who were given the tablets, as opposed to the 1% of women who were administered the placebo.
  
  Mouthwashes can be used to aid the symptoms of dry mouth, but it is vital to not use mouthwashes that contain alcohol as this can further dry out the mouth. Chewing sugar-free gum may also relieve dryness in the mouth.
• Nausea: approximately 10.4% of women given the HSDD/ FSIAD tablets reported the secondary effect of nausea, this was in comparison to the 3.9% of clinical trial patients who were administered the placebo and reported the same.
  
  Essential oils, such as lavender oil, can be used for the relief of nausea. Other methods to ease the symptoms of nausea include drinking clear beverages and eating ginger as well.

CAN YOU ORDER ADDYI ONLINE?

This medication can be purchased through online pharmacies which are a convenient and easy way of buying medications and renewing prescriptions. To buy Addyi online, there are simple navigation steps to follow which will often direct you with the type of information to provide, and the selection which ought to be made.

To select your product, you add the item to the digital cart which is often represented using an image/ icon of a shopping cart. Once you have filled this cart with the items you require, the steps following normally ask you to provide your financial details, to secure payment, as well as your personal details which are required for delivery.

When you order medications online, it is important to ensure that the site you are using is safe and secure, as you are providing sensitive information. Additionally, credible sites are vital to ensure that you are receiving high-quality medicines that will not adversely affect your health or well-being.

YOU CAN BUY AN ADDYI ALTERNATIVE

Alternatives to the medication, Addyi, can also be purchased through online platforms. These are medications which assist in the treatment of HSDD/ FSIAD symptoms, as well as other sexual dysfunctions.

Viagra for women is one such alternative. Viagra, although for the treatment of sexual disorders in men, can also help improve blood flow in women. This improved flow of blood to the genitalia region of women can be useful in treating the symptoms of low libido.

Some of the differences between these brands can include:

• Cost: medications are priced differently and more-often-than-not, a cost effective therapeutic is generally favoured. This is especially significant when the tablets are to be used on a regular dosing regimen.
• Packaging: brands are often identified by their packaging or branding but these differences do not affect the efficacy of a medication. It can, in some cases, affect the cost of the therapeutic.
• Duration of action: some brands can be formulated with longer durations of action and these tend to make them more favourable. However, there are factors which can also affect the duration of action of a medicament and these can include age, bodyweight and the medical condition of the patient.

Whichever brand you choose for the management of HSDD/ FSIAD, when you order online you can conveniently, safely and discreetly receive the treatment you need delivered to your door.

Buy Addyi directly from our homepage today and put an end to FSD/FSIAD.

Content Review Date: July 2022
Next Review Due: July 2023