Sildenafil citrate, the active ingredient in Viagra, is a PDE5 inhibitor that was introduced to the market in 1998. The patent for this well-known medication expired in 2013 and this established a basis for other leading pharmaceutical companies to manufacture generic Viagra and other Viagra alternatives.
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Sildenafil is a less expensive, yet equally safe and effective, generic medication is available at a fraction of the price of the branded version. In online research studies, this medication has been shown to significantly improve sexual wellbeing and confidence among men with erectile dysfunction, or ED. It has been found to be effective in patients with severe ED, and safety as well as efficacy has been demonstrated in long-term studies. In general, it enhances the quality of life for both patients and their sexual partners.
Sildenafil tablets are primarily used to treat ED, also referred to as impotence. According to the Massachusetts Male Ageing Study, ED is a common condition that affects about 52% of men between the ages of 40 and 70 years. When ED happens, men often lose confidence in themselves and this condition can have a negative impact on relationships.
Both physical health issues and psychological problems such as anxiety can cause ED. However, 80% of cases are estimated to be caused by physical conditions and the prevalence generally increases with age. Reduced blood flow to the penile region is the most common cause of ED. This is often the result of diabetes, high cholesterol and hypertension as well as unhealthy choices like smoking and a sedentary lifestyle.
A research study that was published in 2005 took place to gain an insight into the attitudes, beliefs and sexual experiences of female partners of men with ED. In the study, a total of 293 women responded to a questionnaire that assessed the following aspects of their sexual experiences and perceptions:
The study found that women participated in sexual activity much less often after their partner began experiencing ED symptoms. In addition, women whose partners developed ED reported significantly less satisfaction with their sexual relationship and experiences than before the development of this condition. There was also a notable correlation between decreased female sexual satisfaction and the severity of their male partner's self-reported severity of ED.
Women whose partners were currently taking a PDE5 inhibitor like sildenafil tablets, however, experienced a significantly higher level of sexual satisfaction. Men with sexual performance difficulties can use this medication to regain their sexual well-being. Treatment with an effective PDE5 inhibitor usually leads to the following benefits:
In sildenafil reviews, the average rating for this medication is more than 8 out of 10. This generally indicates that most patients have a positive experience when using this treatment. The majority of people report effective results, and most men say it has helped them regain their sex lives. This medication can be taken as needed, so it does not necessarily need to be taken on a daily basis.
This PDE5 inhibitor is generally the first choice for patients, according to various sildenafil reviews from consumers, also supported by medical specialist ratings. It is well known to have few side effects and it normally starts working within 30 to 60 minutes. With e-commerce and the convenience of the internet, you can now buy sildenafil simply by browsing your online pharmacy and adding the product to the online cart. The process only takes a few minutes.
Sildenafil citrate induces its effect by inhibiting the function of a chemical that occurs naturally in the body called phosphodiesterase type 5 (PDE5). As a result, it relaxes the muscles in blood vessel walls and this causes blood vessels to relax and become wider. This action enhances blood flow to the penis, making it effortless for the user to get and maintain an erection.
It is important to understand that this medication will only work if there is sexual stimulation, such as during sexual activity. For this reason, sildenafil tablets will not produce a constant or unwanted erection. When sexual arousal is initiated, this PDE5 inhibitor promotes better blood flow which strengthens and maintains an erection.
These sex pills are available in sildenafil 50 mg and 100 mg tablets. These doses are approved by medical professionals for the safe and effective treatment of ED. It is generally advisable to take the lowest effective dose at the start of treatment. The tablets can be divided into smaller parts to get a lower dose of 25 mg. These three doses typically have the following effects:
Studies have shown that, overall, there is an 82% successful intercourse rate with the use of this ED treatment. A clinical study that was published in 2017 was carried out to investigate the effects of sildenafil 50 mg compared to 100mg.
A total of 3,674 men with ED were involved in the study and they were asked to respond to questionnaires. Altogether, 977 patients were taking 50mg and 2,697 were using the 100mg tablets. Both doses were found to have the following effects:
The patients in the sildenafil 100 mg group, however, were found to have considerably better results than the 50 mg dose group. This was despite the higher rate of health issues among patients in the 100 mg dose group, such as diabetes and hypertension. Patients in the higher dosage group had a better average monthly frequency of sexual activity and satisfaction compared to the 50 mg dosage group.
This ED treatment takes about 30-60 minutes to start working so ideally, it should be taken at least 30 minutes before sexual activity. In addition, there are some circumstances you can avoid to ensure that you do not slow down the absorption rate of this medication:
On average, this medication stays effective in the body for 4 hours, with the strongest effect happening between 30 minutes and 2.5 hours of administration. However, various factors such as age, sildenafil dosage and general health can affect how well this medication works as well as the duration of effect.
A controlled trial took place to investigate the durational efficacy of sildenafil tablets in men with ED. Altogether, 16 patients with an average age of 55 participated in the study. They received sildenafil 100mg or an inactive placebo treatment to take 1, 8 or 12 hours before visual sexual stimulation. The results showed that the average duration of erections with at least 60% rigidity were as follows:
The study concluded that sildenafil citrate improved self-assessed erectile function in men with ED. It also improved objective assessments and these results were obtained using a diagnostic tool that measures frequency, duration and rigidity of erections. The study concluded that this medication may still have a beneficial effect 12 hours after taking a tablet among some patients.
There are potential side effects associated with this PDE5 inhibitor, however, most people will not experience any. In fact, a relatively small percentage of people experience common side effects. The following table presents some of the most common adverse effects and how to avoid, or cope with them:
Common side effect
What should I do if I experience this side effect?
Keep well hydrated by drinking a sufficient amount of water. Although this medication is more effective when taken on an empty stomach, taking it with a light meal can help prevent a headache caused by hunger.
Like other side effects, nasal congestion is usually mild and short-lived. It is caused by the effect this medication has on blood flow and it can be prevented by using a lower dose, particularly at the beginning of treatment.
Nausea may affect some people and this side effect can also be avoided or mitigated by taking the medication with a small meal or reducing the dose.
In clinical studies, the use of this medication has been shown to be safe and well tolerated. A 4-year study that was published in 2007 took place to assess the long-term safety and efficacy of this medication. A total of 979 men with an average age of 58 were involved in the research.
The study found that there was a low incidence of side effects that resulted from a sildenafil dosage change or discontinuation of treatment. In general, participants were satisfied with this medication and long-term use did not lead to tolerability, or reduced efficacy.
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We are dedicated to providing safe, authentic and affordable treatment, plus our service includes access to reliable information and entirely secure transactions. Furthermore, when you buy sildenafil ED treatment from our online pharmacy, expect the following additional benefits:
Besides medication from the Kamagra product line up that contain Sildenafil citrate, customers can also select from our range of alternatives to Viagra such as tadalafil (Cialis) and vardenafil (Levitra) to deal with erection problems discreetly and effectively along with dapoxetine (Priligy) based products to treat premature ejaculation (PE) and help men last longer in bed.
Content Review Date: July 2022
Next Review Due: July 2023
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